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Saturday, May 5, 2012

DEBTORS UPDATE: BANK OF AMERICA RESPONDS!!!

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Applying for Bank of America Student Loans

Many college students are finding that they have many academic funding options ranging from federal loans to private loans. Each has its own advantages and benefits that set them apart from other financing institutions. If you do not know yet, Bank of America has not only established itself as one of the trusted banks in America it also boasts of reaching out to the needs of the prospective college students, particularly those who have dreams of graduating from college or university.

Bank of America has its own student loan division which focuses on addressing the financial needs of college students. They are known to provide valuable assistance needed to apply for student loans. Bank of America is said to offer education loans that are somewhat different from standard loans. It is best that you learn the various differences in detail in order to make an informed decision.

Bank of America Student Loans includes private loan packages. This option includes Education Maximizer Loan which is good for any student that has reasonable credit ratings. This loan package can be used for just about anything that is associated with the educational process. However as with any student loan you must be disciplined in your spending or you will end up out of money and needing another student loan.

Federally based Bank of America student loans are also available and are much in demand. The US Department of Education provides the loan to students that have met the academic and or credit rating requirements necessary to qualify. These loans can be applied for by either the student or the student's parents. Public or federal loans generally have lower interest rates and more flexible terms.

Aside from private and federal loans, Bank of America Student Loans can either be certified or non-certified. Certification in this sense means that the loans have to be certified by your school. Examples of a certified loan from Bank of America are the Bank of America Private Loans and Bank of America TERI Loans. Non-certified loans from Bank of America include CampusEdge Student Loan and the Education Maximizer Loan.

In response to the growing number of students searching for student loans on the web, the Student Banking division of the Bank of America has established a website for use for students who are interested in filing student loan applications. The websites are helpful and are packed full of the necessary information on Bank of America Student Loans. You really need to go a good job of research on every student loan package you are considering. Once you have completed this exercise you most likely find that Bank of America student loans are a great way to fund your college education.

James Kesel, MS, is the publisher of the Student Loan Consolidation Advice website at http://www.student-loan-consolidation-advice.com Providing important information on Student loans and student loan consolidation including how to Bank of America student loans.

Article Source: EzineArticles.com

BREAKING NEWS: Bank of America Having Digital Bank Run, Website Down 6 Days

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Bank Of America - Rewards American Express Card

Bank of America has launched the first credit card, which will be accepted far and wide on the global network of American Express, named the Bank of America - Rewards(TM) American Express Card. Use this card and avail the many benefits offered by both Bank of America and American Express together.

Basic Features

The Bank of America - Rewards(TM) American Express Card equips you with an appealing introductory Annual Percentage Rate (APR) of 0% on balance transfers and cash advance checks for the first 12 billing cycles. Once the introductory rate has expired, you get a very low fixed interest rate on purchases and balance transfers. There is no annual fee and you are given the option to pay over time.

Additional Benefits

Apart from the features above, Bank of America - Rewards(TM) American Express Card presents you with several other facilities, which include:

- Insurances for accident, damage and rental loss, while traveling

- Emergency services such as replacement of prescription, physicians, hospitals, and referrals as well as legal referral services

- Protection against damage or theft of the card

- Extended warranty protection on purchases from scheduled outlets

Rewards Program

The Bank of America - Rewards (TM) American Express Card's reward program gives you a host of benefits as below:

- Every net retail dollar spent on qualifying purchases earns you a point.

- For all dining and travel purchases, you receive double points

- The reward-package also offers you special privileges for traveling and shopping with merchants (who are partners of American Express). It also includes personal concierge services for 24 hours seven days a week.

- You can redeem your earned points for availing a variety of services like hotel discounts, traveling, branded merchandise, gift certificates and can even get cash.

- You are allowed to earn limitless points throughout the year and there are no blackout dates to disappoint you.

Remember your points last up to five years, which is the date of expiry.

Who Will Benefit Most?

This card from Bank of America is specifically for those of you possessing an average credit yet craving for a credit card. With the card, you can relish the flexible options for payment and a monthly revolving balance.

You do expect more out of your credit cards and the rewards program coupled to Bank of America's Credit card promises you just that.

The American Express Rewards card offers you one of the most thriving reward programs currently available with Bank of America. Through the card, you will be able to access special merchant-offers available only with American Express, as well as exclusive travel and purchase features.

Visit Credit-Wisdom.com Unraveling the best in Credit Cards. Click here for Bank of America Credit Cards [http://www.credit-wisdom.com/creditcards/bank-of-america.php] More information on:"Bank of America Rewards American Express" [http://www.credit-wisdom.com/creditcards/info/Bank-Of-America-amex.php]

Article Source: EzineArticles.com

Bank of America refuses to let customers close accounts

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All About Bank of America Credit Cards

Bank of America is one of the leading financial institutions in the US. It is also one of the pioneers that brought a revolution in the international payment system. It is the largest issuer of both debit and credit cards in the US.

Bank of America offers more choices and options than any other financial institutions when it comes to credit and debit cards. It is committed to a 10-year goal to provide $750 billion in investing, lending and community development.

With the merger of MBNA Corporation and Bank of America Corporation, the former has become a part of the Bank of America family of companies. MBNA Corporation is a pioneer in issuing specialty cards for students and business. So the choices are wider and the offers are more exciting and meet all your financial and investment needs.

At present, the privacy policy of the two financial institutions differs and use and service of MBNA credit cards are yet to be integrated with Bank of America. This integration is likely to complete by the end of 2006.

Bank of America credit cards can be categorized into popular cards, reward cards, everyday cards, entertainment cards, college and university cards, cards for charitable causes, sports cards, outdoor and recreation cards, professional and military cards and business cards.

Bank of America Rewards(TM) American Express® Card is one of the popular credit cards issued by Bank of America. It carries no annual fee and has 0% introductory APR on cash advance checks and balance transfer for the first 12 billing cycles. The regular APR is quite low at 7.99%. Other benefits are that you can earn one point on net retail purchase dollar and two points on dining and travel purchases. You can redeem the points earned on stay at partner hotels, brand-name merchandise, and gift certificates.

Reward cards from Bank of America can be further categorized in to general reward cards, travel cards, shopping cards, and automotive cards. PetRewards(TM) Visa is a reward card issued by this bank. One interesting feature of this card is that you can put the picture of your pet on this card. Plus, you can earn points on pet food discount certificates, veterinary services, and shelter donations. There is no annual fee.

'I Love New York Rewards American Express® Card' from Bank of America, an everyday card, has exceptional features like Identity theft recovery and absolute fraud protection, secure online account management, special shopping and travel offers, introductory 0% APR for the first 12 billing cycles. For every dollar spent on this card you earn one point which can be redeemed towards merchandise, airline, and hotels.

'American Diabetes Association Rewards American Express® Card' from Bank of America is a charitable card. It has features such as 0% APR for the first 12 billing cycle, special shopping and travel offers, identity theft recovery and absolute fraud protection. It also carries no annual fee and comes with the flexibility to pay over time. Its reward options include cash back offer, gift card and travel with no blackout dates plus discounts at partner hotels.

Kentucky Derby Visa® credit card is a sports card issued by Bank of America and has features like online account system and 0% intro APR for the first 12 months. It has no annual fee. Earn a point for every dollar spent on this card in net retail purchases and redeem your points for merchandise and other special privileges that include opportunity to obtain Kentucky Derby tickets.

Some popular professional cards from Bank of America are American Institute of Architects card, American Medical Student Association card, American Society of Civil Engineers card, and American Society of Mechanical Engineers card. All these cards have a 0% intro APR for the first 12 billing cycle and special and flexible reward programs.

Bank of America also issues credit cards for small businesses.

CreditMe.com is a free online credit cards review and application website. We offer credit cards selection from visa, master cards, bank of America,discover, American express, citicards, visa credit cards, and many others. We have quite some categories and hundreds of credit cards selection to fit your need. Get bank of America credit card at CreditMe.com now

Article Source: EzineArticles.com

[OFFICIAL] US Uncut "PAY UP!" Flashmob at Bank of America 4/15/11

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Bank of America Credit Cards

The introduction of credit cards has brought a revolution in the payment system. The conventional way of purchasing things with cash is done away with and what can be more convenient than buying items on credit and repaying the amount after a month from the day you have bought the item?

Credit cards have made shopping simple and convenient. And with the number Internet users gradually increasing, the future of online shopping is bright. It is not an exaggeration to say that online shopping is experiencing a boom. In such market condition, the use of credit and debit card is going to increase manifold. Buying items and services over the Internet saves time and energy. Rather than standing in a long queue, you can book your tickets or buy things with just a few clicks on your mouse.

One of the market leaders of credit card issuers is Bank of America. In fact, Bank of America is the largest issuer of credit cards in the US. It has surpassed its nearest rival J.P. Morgan Chase as the largest credit card issuer after its merger with one of the leading credit card issuers - MBNA.

With this merger, Bank of America Card Services organization has more than 40 million active U.S. accounts. It is worthwhile to take note that Bank of America is also the largest issuer of debit cards.

Bank of America credit cards are one of the most flexible credit cards in the market. Its credits cards are designed to suit extensive credit situations and special needs of students and big businessmen.

One of the most interesting features of Bank of America credit cards is its low Annual Percentage Rate (APR). Though some of the Bank of America credit cards have introductory APR, they are quite low, which is usually 1.9% for a period of usually 6 months. It's quite a good deal if your regular APR is fixed at 6.99% even though there is an introductory APR of 1.00% for a period of 6 months. Most other credit cards issued by Visa and MasterCard have higher regular APRs.

For example, Mexicana® Airlines Visa® Platinum has a regular APR which is 6.99% and an introductory APR which is fixed at 1.9%. Though it carries an annual fee of $45, its benefits are immense. After your first purchase, you receive 1 free companion ticket coupon. Thereafter, you will receive a $99 companion ticket coupon each year. You can also earn 1 Frecuenta Mile for each dollar spent and 2 Frecuenta Miles for every dollar spent with Mexicana Airlines. Each year you will receive 2,000 anniversary mile and 4,000 Welcome Miles after you have joined the Frecuenta Program. These miles can be redeemed on Mexicana or on any of its 15 partner airlines.

On the flip side, most of the Bank of America credit cards carry an annual fee. Like any other credit cards, Bank of America credit cards have reward cards, credit cards for students, corporate etc. Its cards are also designed to serve the different needs of its diverse range of customers. It has reward programs designed for air travelers and frequent shoppers. In additions some of its credit cards has additional benefits and perks.

Though Bank of America is the largest issuer of credit and debit cards, it does not have its own electronic payment processing network. It pays fees to card issuers Visa and MasterCard to process charges made with cards issued by Bank of America. After MBNA merged with Bank of America, it is considering acquiring its own electronic payment processing network. If it succeeds in doing so, it will no doubt emerge as a serious competitor to market leaders Visa and MasterCard.

With the merger of MBNA, Bank of America credit cards have also acquired a new dimension. MBNA was the pioneer in issuing specialty credit cards to universities, colleges, and business. It is sure to the break the market monopoly of Visa and MasterCard.

CreditMe.com is a free online credit cards review and application website. We offer credit cards selection from visa, master cards, bank of America,discover, American express, citicards, visa credit cards, and many others. We have quite some categories and hundreds of credit cards selection to fit your need. Get bank of America credit card at CreditMe.com now.

Article Source: EzineArticles.com

Bank of America Parody

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Bank of America Review - Big Bank Can Bring in Customers - Can it Keep Them?

Bank of America, headquartered in Charlotte, North Carolina is a banking giant. As a big bank, second in holdings only to JP Morgan Chase, Bank of America attracts many customers because of the vast number of locations and the huge offering of services of products. Some customers seek out big banks like Bank of America for the feeling of security; others become customers by default as Bank of America gobbles up other institutions like Merrill Lynch and FleetBoston Financial Corp. Many customers are drawn to the competitive rates of Bank of America and others are lured in by special online deals and gifts. So Bank of America now has over 53 million customers including individuals and businesses but are Bank of America customers "happy customers?'

Bank of America's Comprehensive Products are a Plus

Bank of America is no doubt a full service bank offering about any financial product a banking customer could desire including checking accounts, savings accounts, home loans, school loans, car loans, business loans, certificates of deposit, credit cards, brokerage services and much more.

Bank of America's Customer Service Options:

Bank of America has branches in most medium to large cities in the United States. They also have a website, bankofamerica.com, for account access and bill pay. The website also offers a myriad of customer service phone numbers.

Can Customers have a "Happy Meal" at a Super-sized Bank?

Most customers are happy with the selection of products offered by Bank of America. Those with good credit have found it easy to get competitive rates. Many have taken advantage of temporary low rates, made at least the minimum payments on time and paid off the balance before the rate skyrocketed. These are the happy customers.

While the products are vast and the rates are competitive, many customers share the same stories of customer service frustrations. Unhappy customers are blasting away in forums about negative experiences with phone calls to Bank of America customer service reps.

Our own experiences with Bank of America have included phone calls resulting in long holds, many transfers, unresolved questions and customer service reps that seem to want to pass us off.

On the other hand, our experiences with the Bank of America web site have been favorable. It is easy to access, easy to use and fast.

Bank of America also offers many cash incentives to bring in new customers. As with all fine print, with Bank of America you'd better read it carefully. For example, a $50.00 cash gift for opening a new account will only be made 50 days later and sometimes standard fees reduce the "gift" before you ever get it.

Bank of America recently announced Brian Moynihan as the new CEO. Moynihan admits, "We have a lot of work to do, and I'm ready."

Bank of America has an impressive number of services and products but unfortunately, many customers just feel like a number, and not a very high one, when dealing with this big bank.

Jonathan Kraft is a recognized expert in helping consumers save money, shop safely and be protected from identity theft. Learn more about the money saving strategies and consumer protection at the Identity Theft Secrets blog.

Article Source: EzineArticles.com

Tuesday, May 1, 2012

Money Transfer Services - Convenient and Reliable

Money, perhaps the most significant invention of mankind, has been a major force behind the development of trade. Before the advent of money people used to rely on barter system, in which people used to exchange goods for goods. The acceptance of money as a source for trade has led to the need to transfer money from one location to another. The quest to create some effective money transfer system always propelled people on digging deep for better solutions. The necessity eventually led to the evolution of various money transfer services. Also the expansion of the global economy and migration of people provided the much needed impetus for money transfer services that led to the advancement of different forms of money transfer services.

Today there are various media through which money can be transferred to different locations, and each method has its own benefits. Services like wire transfer, money order, bank draft, instant money transfer and internet money transfer are the various methods that are now used to transfer money. What medium of money transfer is more effective vary according to the requirements and convenience of individuals.

Wire Transfers: Before the inception of computerised banking systems, the world needed a secure method to transfer money from one location to another. This brought wire transfer into context, which over the years has been the common method of transferring money from one bank account to another and in fact the best way to send money. Though the "wire" involved has developed from old world telegraph wires to modern fiber optic cable, the term "wire transfer" has stuck around because the service provided remains essentially the same since its inception. The wire transfers are considered safe and convenient because bank/financial institution verify both the sender and the receiver's account details and neither of them can stay anonymous. The sender needs to provide his/her account number and the receiver's account number to the bank/financial institution to transfer the amount. After bank/financial institution receive the account number it transmits the message through SWIFT which is the acronym for Society for Worldwide Interbank Financial Telecommunication (allows bank/financial institution to exchange financial data i.e. data regarding money transfers, account status etc.) to the receiver's bank with the payment instructions.

Money Order: A money order is a payment order usually issued and payable at a bank or post office. The sender has to fill a form that includes name, address, amount to be sent along with the recipient's name and address. The sender can also write a short message as there is a provision for it on the money order form. The advantage of sending a money order is that the receiver or the sender doesn't require a bank account. In some countries international money order services are also available, which is similar to a regular money order, except that it can be used to make payments abroad.

Bank Draft: A bank draft or Demand Draft is issued by a bank or any other money transfer company and is cashable at any banking institution. This type of money transfer service is generally preferred by large sized business houses and institutions due to additional security and audit trail features. The main feature of the bank draft is that the amount is already paid for in full before the draft is issued, ensuring its clearance and credibility.

Instant Money Transfer: This facility enables the sender to transfer money anywhere in the world within minutes without the use or need of a bank account. The sender needs to produce his/her original identity document to the bank/financial institution from where he will be doing the transaction along with the phone number (but not mandatory) of the receiver; the amount that the sender wants to transfer to the receiver including the location where the amount needed to be transferred.

Internet Money Transfer: Internet has made the money transfer service more convenient and hassle-free. Today sending money anywhere in the world is just a matter of few clicks. With Internet money transfer services anyone can send money to anywhere in the world within a span of a few minutes. To avail the service you need to have an online Login ID and password (provided by the bank/financial institution). You also need to register receiver's name, bank account number and the branch location to make online transaction.

Article Source: EzineArticles.com

Lego 3661 Review Bank & Money Transfer City

Bank It Blogger

Money Transfer Companies Fees Compared

Here is a money transfer comparison of the different methods to transfer money and some of the main companies offering such services. The three main methods for transferring money overseas are: cash transfers, money orders and bank transfers.

Cash Transfers

These are done by specialist companies that are able to transfer money around the world quickly and efficiently. Here are some of the main money transfer companies and also there fee for a $300 US money transfer from America to the Philippines.

Western Union are one of the leading companies in this field. They have a huge network of over 245,000 agents in over 200 countries all over the world and can boast a revenue of over $4 billion US. Besides money transfers they also offer a messaging service.

Transfer fee: $16 for the money in minutes service.

Moneygram has over 125,000 locations worldwide. There online service allows anyone to transfer money around the world within minutes. They also offer services to pay utility bills in the US from abroad.

Transfer fee: $9.99 for the ten minute money transfer service.

Xoom, another growing money transfer company whilst not being as established as the leading brands yet offers very competitive low money transfer fees. You can make payments online via PayPal, any major credit card or alternatively you can have money withdrawn straight from your bank account.

The recipient can choose to receive the money in either US dollars or local currency.

The slight limitation with Xoom currently is that they only services to the following 30 countries. They are:

Argentina, Australia, Bangladesh, Bolivia, Brazil, Canada, Chile, Colombia, Dominican Republic, Ecuador, El Salvador, Germany, Guatemala, Honduras, India, Jamaica, Mexico, Morocco, Nepal, Nicaragua, Panama, Paraguay, Peru, Philippines, Poland, Sri Lanka, United Kingdom, United States, Uruguay, and Vietnam.

Transfer Fee: $14, however a value service for 7.99 is available whereby Xoom makes an electronic withdrawal from your bank account, which has to be based in the US. The transfer may take up to four days to go through for new customers due to several set-up procedures that have to be completed. Xoom also offer a money delivery service whereby recipients can have the money physically taken to their house or business.

Money Orders

In America it is possible to get a money order issued from the US Postal Service.

The normal limit for a money transfer is $700 for each money order although you may buy multiple money orders per day totaling up to $10,000. The fee per money order is variable from between $3 to $9. A money order from the US can be converted to money at most major banks and financial institutions around the world. Each money order is traceable via its unique money transfer reference number. Most banks are able to issue money orders of up to around $1000 they will also have a fee of approximately $10 pre money order.

Bank Transfers

Banks usually offer several ways to transfer money. However all banks are different so you would have to check locally to find out what services are available.

One method would be to simply send a cheque overseas. However the bank where the recipient tries to cash the cheque may well hit them with a large fee possibly around $50 and they may also have to pay a fee for the money to be converted into the local currency. Checks can also take up to six weeks to cash

Another method is to do a wire transfer. You can do one of these even if you do not have an account with a bank but the recipient must have access to a corresponding bank where they can collect the money transfer. Wire transfers can be done almost immediately but you would need to pay in cash when you do it. The fee varies from bank to bank but usually they cost around $65 for non-account holders and approximately $40 for existing account holders.

So those are the main methods of money transfer outlined and some of money transfer companies fees compared. Prices may also be different depending on both which country you are sending from and also which country the money will be collected in. Please make sure you are clear on exactly what exchange rate you are paying as this can add greatly to the real cost of the transfer.

One final option that you may wish to pursue is that of finding a credit card that has low transaction fees for making withdrawals abroad. You could open a joint account and let the recipient take the card with them abroad and you simply foot the bill in your country. Of course a high degree of trust is required for this method but it is worth looking into.

There are many money transfer options and the lowest costing service is not always the best option so shop around and find which company offers the best and most convenient service for you.

Money Transfer Review provides free money saving comparison charts, safety tips and money saving advice for all your money transfer needs. Simply click: Money Transfer to discover more.

Article Source: EzineArticles.com

Tranzfers - Cheaper and Faster Way to Send Money Overseas

Bank It Blogger

Money Transfer Advice For Security And Savings

With over 175 million people living outside of their country of origin, the growing usage of migrant workers and the continuation of globalisation the money transfer market looks set to continue its current growth levels of 10-12% per year. Currently the market is already worth over $250 billion with more and more companies organising new and innovative services for transferring money alongside some more traditional money transfer companies.

Some of the more well known money transfer companies are: iKobo, Western Union, ICICI, MoneyGram and E-gold. For newcomers to the money transfer market it can be a little overwhelming at first. There are a variety of methods that these companies use to transfer the money not to mention bank transfers and paper transfers. For this reason it is important to make an informed choice about who you are going to transfer your money with, it is far better to make an informed and safe judgment than to just use the first money transfer company that you come across.

Whilst we all want to get the best value for money transfer it is a good idea to remember that the cheapest option is not always the best option. With that in mind here are a few points worth bearing in mind whilst arranging your money transfer:

What exactly is the money transfer fee and how is it calculated?

What is the exact exchange rate that they are using?

How will the money actually get into the hands of my intended recipient?

How soon will the funds be made available?

Is it possible for the recipient to be able to collect the funds from different locations?

Are there any extra fees for using credit cards? Exactly how much will they come to?

If they are able to answer the above questions quickly and easily then the chances are the company are well organised and capable of transferring your money. However save your receipts - all signed documents are proof of the money transfer and would be useful if there was to be a dispute.

Furthermore here are a few more questions you may wish to ask the company:

If the money is not received by the specified time/date will I receive any compensation?

What rights do I have if this situation were to occur?

Does the recipient have to pay a fee as well?

What rights do I have if the money is not received at the promised time?

If the recipient is unable to pick up the money transfer for some reason, what is the refund policy?

What ID is acceptable for the recipient to provide in order to collect the money transfer?

Now of course having dealt with the safety concerns how about saving a bit of money as well. Here are a few top tips to consider:

Consider a delayed transaction. These are often significantly cheaper the only difference is the money transfer can take 2-3 days. This should not be a problem if there is no emergency.

Think about performing a direct bank to bank transfer although generally these are slower this can often save a considerable amount, consult your local bank for details of any particular bank codes that you may need.

Don't forget to watch out for hidden exchange rate costs. This is often where the money transfer companies will make their money on you. They don't always make it clear exactly how much they are charging and for what.

Be aware that different companies charge more money for sending to different locations so depending on your situation this could increase the fee dramatically.

Try not to use a credit card if possible as this may also add an extra charge for you as you will have to pay the cash advance fee. Furthermore try and find a company that offers a flat rate fee as opposed to a money transfer company that charges a percentage as this tends to be a better deal.

Finally, Check the newspaper or online for the latest rates and cross check them with what the company are offering you. You may find you are losing money compared to what you should be getting so don't be afraid to find a new company if this is the case.

There are a lot of new companies starting all the time and a great variety of ways for you to transfer your money so make sure you check out all the competition to find the one that suits you most, your needs and your budget. So having considered all the above safety factors and money saving tips there is no reason for you not to be able to transfer your money in timely and cost-effective manner.

Money Transfer Review provides FREE money saving comparison charts, safety tips and money saving advice for all your money transfer needs. Simply click: Money Transfer to discover more.

Article Source: EzineArticles.com

Wednesday, January 4, 2012

Fwd: | 12.13.11 | Alexza clears a big hurdle in its path to FDA OK; Startup banks $20M for therapeutic vax



-------- Original Message --------
Subject: | 12.13.11 | Alexza clears a big hurdle in its path to FDA OK; Startup banks $20M for therapeutic vax
Date: Tue, 13 Dec 2011 13:04:34 -0500 (EST)
From: FierceBiotech <editors@fiercebiotech.com>
Reply-To: editors@fiercebiotech.com
To: nbrauchitsch@yahoo.com




December 13, 2011

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Today's Top Stories
1. Alexza shares spike after antipsychotic wins weak embrace from FDA panel
2. Cambridge, MA startup snags $20M for therapeutic vaccine program
3. Catabasis boosts Series A to $47.6M as it zeroes in on Amarin rival
4. Setbacks force AVI BioPharma to ax staffers in restructuring effort
5. YM gets boost after posting promising anemia data on myelofibrosis drug

Also Noted: Samsung Biologics
Spotlight On... Quintiles launches CRO in booming China drug market
Merck gains rights to diabetes drug portfolio; 5-year Velcade data points to improved survival benefit for myeloma patients; and much more...

More Fierce Life Sciences News:
1. Protein 'switch' could be key to fighting obesity, diabetes
2. Supreme Court considering crucial gene patent case
3. Pfizer elects CEO Read as company chair


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Today's Top News

1. Alexza shares spike after antipsychotic wins weak embrace from FDA panel

By John Carroll Comment | Forward | Twitter | Facebook | LinkedIn

Alexza Pharma ($ALXA) just barely managed to clear one of the big hurdles that threatened to once again block its marathon effort at winning an FDA approval of the inhaled antipsychotic treatment Adasuve (formerly AZ-004). An expert FDA committee voted 9 to 8 in favor of an approval yesterday evening, with a number of critics clearly remaining unhappy with the safety issues that have hobbled the program before.

Just days ago investors were dumping shares in Alexza after reading regulators' concerns about the potentially lethal pulmonary effects of the treatment in patients with asthma or COPD. Those same risks persuaded the FDA to reject Alexza's initial try at an approval. But a majority of the FDA panel felt that the biotech's risk mitigation strategy, which would demand that patients are carefully screened and then monitored for the first hour after treatment, satisfied their safety concerns.

"This product offers the potential to be a significant contributor to an important need," noted Andrew Winokur, director of psychopharmacology at the University of Connecticut School of Medicine in Farmington, according to a report from Bloomberg. Alexza provided "impressive efficacy data."

Adasuve is a vaporized version of the old antipsychotic loxapine. Inhaling it with the use of a new device developed by Alexza offers a quick method for dealing with bouts of schizophrenia and bipolar mania. But a number of specialists in the FDA remain worried that the drug could wind up in the wrong hands, or administered without all the necessary precautions.

Investors, who have alternately fled and embraced Alexza's shares, initially responded to the positive vote by pushing its battered shares up more than 70%. By mid-morning some of those gains had been given up as analysts considered Alexza's chances at finally winning an approval from a skeptical FDA. Some analysts say an approval could pave the way to a market worth about $150 million in annual revenue.

Alexza now faces a PDUFA deadline on February 4.

- read the press release
- here's the report from Bloomberg

Related Articles:
Alexza Pharma shares tank on FDA's safety concerns about Adasuve
Alexza shares plunge after it offers new timetable for AZ-004

Read more about: schizophrenia, Alexza Pharmaceuticals, Bipolar disorder, Adasuve
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This week's sponsor is Perceptive Informatics.

You asked for it...DataLabs EDC - Designed for you!



2. Cambridge, MA startup snags $20M for therapeutic vaccine program

By John Carroll Comment | Forward | Twitter | Facebook | LinkedIn

After importing the IP for a new therapeutic vaccine that promises to desensitize celiac disease patients to the toxic effects of gluten, the newly established ImmusanT has rounded up $20 million from a single investor to back its mid-stage clinical development work.

Launched in Cambridge, MA last March, ImmusanT quickly attracted attention from the biotech community for Nexvax2, which pooled three gluten-derived peptides into an injection for celiac patients. Drawing on the work of the company's scientific founder, the Australian Bob Anderson, who folded his biotech down under and relocated to the U.S. to work with ImmusanT co-founder Leslie Williams, the startup quickly pushed through Phase I with the backing of angel investors.

All the money for the Series A is coming from Vatera Healthcare Partners, which also backed Pearl Therapeutics. And ImmusanT is working with Inova to develop a diagnostic that can be used to ID the celiac disease patients able to benefit from the therapeutic vaccine.

"There is tremendous enthusiasm for Nexvax2 from celiac patients and clinicians who want a therapy that allows patients to resume a normal diet and return to good health and improved quality of life," Williams said in a statement. "The financial backing and support of Vatera Healthcare Partners will allow us to round out our team and advance our research and development programs to bear out this hypothesis."

- here's the press release

Read more about: celiac disease, ImmusanT
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3. Catabasis boosts Series A to $47.6M as it zeroes in on Amarin rival

By John Carroll Comment | Forward | Twitter | Facebook | LinkedIn

Cambridge, MA-based Catabasis Pharmaceuticals has scored an additional $8 million for its Series A, pushing the first round to $47.6 million as the developer advances a second omega-3 drug program through a Phase I study ahead of schedule.

Back in 2010, when Catabasis was named a Fierce 15 company, CEO Jill Milne's timeline called for a second program to get underway in 2012. But backers at SV Life Sciences, Clarus Ventures, MedImmune Ventures and Advanced Technology Ventures have opted to gas up early to fuel clinical work on CAT-2003, an early-stage omega-3 conjugated compound designed to fight hypertriglyceridemia--the same cardiovascular target Amarin ($AMRN) is zeroing in on with the closely watched AMR101. Catabasis's first omega-3 drug program is focused on diabetes, which is slated to move into a mid-stage study in the first half of next year.

"In CAT-2003 we identified a molecule in preclinical studies which is superior to anything we've seen out there in the clinic," says company co-founder Mike Jirousek, making it clear that the biotech believes it has the potential to take on Amarin's treatment if AMR101--designed to extract high levels of fat in the blood--goes on to win an approval. "This is a new option for hypertriglyceridemia. The data has been so exciting around the second program, it's something I think everyone wants us to pursue in parallel rather than in tandem."

Catabasis has been growing at a brisk pace, bringing their staff numbers up to 20 over the past year and planning another 10 hires or so by the end of next year, says Milne. Next year the biotech will look for a potential partner on the diabetes program, and the CEO notes that the deal numbers would influence whether--and how much--Catabasis might seek in a Series B round.

- here's the press release

Special Report: Catabasis Pharmaceuticals - 2010 Fierce 15

Related Article:
Catabasis lands $14.5M tranche for Omega-3 drug development

Read more about: Diabetes, Amarin, Catabasis Pharmaceuticals
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4. Setbacks force AVI BioPharma to ax staffers in restructuring effort

By John Carroll Comment | Forward | Twitter | Facebook | LinkedIn

RNA drug developer AVI BioPharma buried the lead in a press release Friday. After touting a new hire--Jayant Aphale, Ph.D.--at some length, the Bothell, WA-based biotech tersely noted that 28% of the company's workforce was being axed in a restructuring. That move will cost the jobs of about 35 of the 125 staffers at the company, which has been dealt a pair of painful setbacks in recent months.

AVI missed out on a $500 million government contract for an RNA-based pandemic flu treatment, notes Xconomy's Luke Timmerman, who first ferreted out the news yesterday. And then the biotech was dealt another blow when it failed to overturn a patent claim by Prosensa that it owns a stake in AVI's lead muscular dystrophy program.

"With our stock price at 52-week lows, and the recent disappointing news of not getting the flu contract, combined with Prosensa's success in defending their patent in Europe related to Exon 51 (our lead program), we felt it was important to reprioritize/refocus on the primary value-driving programs of DMD, Ebola, and Marburg," AVI CEO Chris Garabedian told Timmerman in an email.

In its statement, AVI noted that the layoffs will help the developer focus more on rare and infectious diseases. Its lead RNA program is targeted at Duchenne muscular dystrophy and AVI is pursuing other programs for Ebola and the Marburg virus. A number of RNA companies have been struggling to raise funds recently as Big Pharma players exited the field.

- read the press release
- here's the Xconomy story from Timmerman

Related Article:
Investigators herald antisense breakthrough on muscular dystrophy

Read more about: AVI Biopharma
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5. YM gets boost after posting promising anemia data on myelofibrosis drug

By John Carroll Comment | Forward | Twitter | Facebook | LinkedIn

Shares of YM Biosciences ($YMI) got a bump this morning after several analysts gave the developer a pat on the back for the updated midstage results released for its myelofibrosis drug CYT387, a JAK1/JAK2 inhibitor.

TheStreet's Adam Feuerstein started the round of applause this morning, noting that the developer's drug maintained a positive anemia response, with about half of the 68 myelofibrosis patients in the study who were transfusion dependent at the launch of the study becoming transfusion independent for at least 12 weeks during treatment. And of the 26 transfusion-dependent patients getting the 300 mg dose, 62% were transfusion independent for 12 weeks. Both groups maintained hemoglobin levels at or above 8 g/dl.

"These '387 anemia response data are stronger and more credible than what was presented last spring because Monday's results are culled from many more patients enrolled at multiple clinical trial sites," notes Feuerstein. And producing the positive anemia response after significant doubts had been raised will help favorably position the drug against rivals on the market."We expect these results to accelerate partnership discussions, and are increasingly optimistic about the potential of CYT387 in other hematologic indications," wrote analyst Avik Roy.

"In this multicenter study, CYT387 continues to demonstrate a unique ability to render and maintain myelofibrosis patients transfusion independent for clinically-relevant periods, while also producing significant and durable improvements in their splenomegaly and constitutional symptoms," said Dr. Nick Glover, the CEO of YM BioSciences. "In addition, MRI results obtained from a subset of subjects confirm the meaningful improvements in splenomegaly as measured by palpation. Moreover, CYT387 was well tolerated, with dosing up to and exceeding two years."

- check out the YM release
- here's the story from TheStreet

Related Articles:
YM BioSciences inks deal to acquire Cytopia
YM withdraws European app for nimotuzumab
FDA lifts clinical hold on YM therapy

Read more about: YM Biosciences, CYT387, myelofibrosis
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Also Noted

This week's sponsor is Samsung Biologics.

SPOTLIGHT ON... Quintiles launches CRO in booming China drug market

In yet another sign of the eastward drift of clinical development work, Quintiles says it is setting up a new CRO in China to help developers with everything from clinical trial management to regulatory submissions. The move comes as Quintiles, which has a staff of 300 in the Asian country, is planning to double the number of workers it has there. "We have an aggressive growth plan for China," says Quintiles China GM Ling Zhen. Release

  @FierceBiotech: Leave it to engineers to come up with a potentially novel solution to fight Alzheimer's disease. Article | Follow @FierceBiotech

  @JohnCFierce: Quintiles sets up a China CRO, plans to double staff in China--another step in the shift to the East. News | Follow@JohnCFierce

  @RyanMFierce: Avila makes progress with Btk inhibitor, same type of drug as $JNJ shelled out $150M for last week. Story | Follow@RyanMFierce

  @MaureenFierce: Fooling immune system reverses multiple sclerosis in mice, according to a University of Freiburg study. More | Follow@MaureenFierce

  @MarkHFierce: Look at this--gene therapy works! Sometimes the most interesting news comes out during the weekend. Item | Follow@MarkHFierce

> Merck's grabbed worldwide licensing rights to a portfolio of Type 2 diabetes treatments held by Japan's Mochida Pharmaceutical. Release

> Takeda has presented 5-year follow-up data demonstrating that Velcade added to standard treatments reduced the threat of death by 31% among untreated multiple myeloma patients. Story

> Astellas and Optimer won European approval for the new antibiotic Dificlir. Story

> Palo Alto, CA-based Anacor says that that it has nailed down positive Phase IIa its two PDE-4 inhibitors, AN2728 and AN2898, in mild-to-moderate atopic dermatitis, a chronic rash. Release

> The FTC has approved Valeant's acquisition of units of J&J and Sanofi. Story

> Fitzsimons Redevelopment Authority says it will add an $8 million, 37,000-square-foot facility at the Bioscience Park in Colorado to house startup biotech companies. Story

Pharma News

  @FiercePharma: SEC accuses Stiefel Labs, ex-chief of fraud: NYTNews | Follow@FiercePharma

> Watson takes big initial chunk of generic Lipitor sales. Report

> Pfizer elects CEO Read as company chair. Report

> FDA rejects citizen's petition on Plan B. News

> SEC accuses ex-Stiefel CEO of fraud. Article

> J&J to release new Doxil batches. Story

Biotech Research News

> Antibody may help fight Alzheimer's. More

> Protein 'switch' could be key to fighting obesity, diabetes. Story

> Gene therapy appears to work for hemophilia B patients. Report

> Supreme Court considering crucial gene patent case. News

Pharma Manufacturing News

> Actavis, Mylan continue defense in Digitek API suits. Article

> Packaging veteran urges including patient in drug pedigree chain. More

> KV reports doubt about viability under decree. News

> Europe issues 2nd recall of drugs made by Ben Venue. Story

And Finally... Investigators at the Mayo Clinic and the University of Georgia say they have developed a new vaccine that proved highly effective at reducing breast and pancreatic cancer tumors in mice. Release


Webinars


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> Drug Development: An Overview of the Regulated Clinical Trials Process Used to Bring a New Drug to Market Dec 13, 1 pm ET/10 am PT

Join us for a one-hour overview of the regulated clinical trials process used to bring a new drug to market. Topics include: Clinical Trial Considerations, Phase 1, Phase 2a and 2b, Phase 3 and 3b, Phase 4, Pharmacoeconomics, Risk Management Plan and more. Register today.



Events


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> Patheon Seminar: Moving from Molecule to Clinical Trial - December 13, 2011 - San Diego, CA

Four scientific leaders will help you navigate through regulatory obstacles, give you tips for getting your molecule to clinical trials more efficiently, and provide practical case studies that demonstrate how others molecules have successfully moved to clinic. Learn more here.

> Just Released: New Trends in Preventive and Therapeutic Vaccine

This new Insight Pharma Report analyzes current R&D activities and commercial prospects for vaccines. Sectors covered include bacterial infections; viral infections including hepatitis, HIV, influenza, and others; autoimmune diseases, cancer, and many more. For more info, www.insightpharmareports.com

> Webinar: The Benefits of Web-Based ePRO for Phase IV Clinical Studies - December 15, 2011

On Dec 15, 2022, learn how to collect high quality PROs in late phase studies, and how to engage patients online to increase compliance and retention. Register for this educational webinar from CRF Health.

> Rutgers Mini MBA: BioPharma Innovation & BioPharma Entrepreneurship Programs

Focused learning for science & business professionals to expand business knowledge, creativity and decision making skills in the Biotech & Pharmaceutical industries. Sessions start in January 2012. Learn more at www.cmd.rutgers.edu/mini-mba-biopharma.html. Call 848-445-5526 or biopharma@cmd.rutgers.edu.

> Webinar: JHU's Master's in Biotechnology Enterprise & Entrepreneurship

Learn more about Johns Hopkins University's 10-course graduate program that is designed for those seeking to pursue a biotechnology entrepreneurial career beyond the laboratory. The entire degree can be completed online. Available On-Demand | REGISTER NOW

> Online GMP Courses Priced as Low as $75 for Individual Learners

Our web-based GMP courses can be purchased online and taken at your own pace. Once completed with adequate proficiency, you'll receive a certificate of completion. Developed by GMP experts and taken by thousands, these courses provide quality GMP training for far less than other alternatives. Click Here

> Partnerships in Clinical Trials 2012 - March 4-7 - Orlando, FL

Partnerships is the largest clinical trial operations, development and outsourcing meeting in the world with over 1500+ attendees and 200 exhibitors. This leading event is a unique senior leadership meeting focused on overcoming challenges clinical trial executives face. Visit www.cliicaltrialpartnerships.com.

> The Industry's Best Kept Secret: BioNetwork East - March 5-7 2012 - Miami, Florida

BioNetwork East is an elegant and intimate retreat for BioPharma business development executives to explore opportunities in partnering & funding. Visit www.bionetworkeast.com and use code BE12Fierce to save$825 - our best offer!

> Comparative Effectiveness: A Real-World User's Guide - March 14-15, 2012 - Washington, DC

Moving from Policy to Practice in Research and Delivery! Push beyond basic questions to evaluate the importance of comparative effectiveness research (CER) and provide participants with actionable understandings of how CER evidence can be better managed and developed within their own organizations. This event will provide participants with a "what does it mean for me" perspective on CER and HTA, providing take-aways to apply within day-today drug development and marketing positions. Register Today!



Marketplace


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> Digital Health Technology: A Guide to Medtech's Biggest New Player

Are you up to date on the latest in digital health technology? Let Elsevier Business Intelligence guide you in navigating this growing field. This report covers new technology and policies that could affect your bottom line. Learn more at http://pages.elsevierbi.net/digitalhealth/



Jobs


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> Director, Reagent Manufacturing & Operations - San Francisco, CA - Fluidigm

Directly reporting to the VP of Manufacturing, the Director will be responsible for managing and directing Fluidigm's Reagents and Assays Manufacturing operations. This includes formulating manufacturing operations strategies in support of business goals and objectives, developing and mentoring manufacturing employees and driving continuous improvements to achieve optimal operational efficiency. He or she will set up the systems and tools to deliver quality products and services that will meet customers' expectations in the most cost-effective manner. The Director will also lead and manage the supply chain operations in South San Francisco which includes but is not limited to: purchasing, inventory management, supplier management... Learn more.

 

> Sr. Product Manager – NJ – Celgene Corporation

Celgene Corporation is a global biopharmaceutical company that is helping to turn incurable cancers into chronic, manageable conditions. An ideal candidate for this position will have BS/BA degree and a minimum of 7 years' pharma/biotech industry and 3 years product management/marketing research. Sales experience in the pharmaceutical industry required. The Sr. Product Manager assists in the development and implementation of marketing and educational programs, leading segments of the projects as appropriate. Also participates in the development of business plans, product strategies, and tactical implementation.....Learn more.

> Manager, Strategic Forecasting & Analytics Job – NJ – Celgene Corporation

Celgene Corporation is a global biopharmaceutical company that is helping to turn incurable cancers into chronic, manageable conditions. An ideal candidate for this position will have BS/BA degree. The Manager, Strategic Forecasting & Analytics will provide ongoing forecasting and long-range analytical support for the Americas Hematology/Oncology business. The Manager will participate on cross-functional teams including marketing, market research, new product planning, sales operations, business development, manufacturing, finance, and strategic planning....Learn more.

> Business Analyst - Gaithersburg, MD - MedImmune

MedImmune is a company that shares your passion for helping to improve human health around the world. Explore a MedImmune career as we strive to better more lives, more often, around the world. The Business Analyst works as a liaison among stakeholders in order to elicit, analyze, communicate, and validate requirements for changes to business processes and information systems. The role is responsible for understanding and documenting business requirements for specific business problems, translating business requirements into functional specifications, and verifying that solutions meet the requirements...Read more.

> IT Infrastructure Portfolio & Planning Analyst - Gaithersburg, MD - MedImmune

MedImmune is a company that shares your passion for helping to improve human health around the world. Explore a MedImmune career as we strive to better more lives, more often, around the world. The Senior Analyst, IT Infrastructure Portfolio & Planning is responsible for the planning, management, and execution of capacity planning, forecasting, and requirements definition for all IT infrastructure domains including LANs, WANs, servers, storage, telephony, etc. Candidates should have at least five (5) years of experience in the area of analytic and/or discrete event simulation modeling...Read more.

 

> Senior Manager, Information Architect - Gaithersburg, MD - MedImmune

MedImmune is a company that shares your passion for helping to improve human health around the world. Explore a MedImmune career as we strive to better more lives, more often, around the world. This position requires at least 8+ years of work experience in an Information Systems and 5+ years of experience in Information management functions. Responsibilities include developing and evangelizing Enterprise Information Architecture and providing leadership for developing and maintaining the Enterprise Information Architecture...Read more.

> Systems Analyst - Gaithersburg, MD - MedImmune

MedImmune is a company that shares your passion for helping to improve human health around the world. Explore a MedImmune career as we strive to better more lives, more often, around the world. The Systems Analyst enables the technical delivery of projects with adherence to defined technical standards and provides support for domain and enterprise applications. This position requires 3 or more years of relevant work experience including business analysis, testing / quality assurance, Application Development and Operations...Read more.

> Data Center Fac.Engineer– Gaithersburg, MD - MedImmune

MedImmune is a company that shares your passion for helping to improve human health around the world. Explore a MedImmune career as we strive to better more lives, more often, around the world. The Data Center Facilities Engineer will support MedImmune, Inc. data centers (DC), main distribution frames (MDF), intermediate distribution frame (IDF), throughout MedImmune, Inc. Global Sites. This position requires 5 or more years of experience in an industrial setting. (DATA Center or Critical Environment experience Preferred)...Read more.

> Need a job? Need to hire? Visit FierceBiotech Jobs

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